Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

is an aldosterone blocker that works by binding at the mineralocorticoid receptor. It has some similarities to the potassium-sparing diuretic spironolactone, but rarely causes gynecomastia.

Spironolactone, the first-line treatment ... Given her hypertension and hypokalaemia, adrenal function testing was obtained. Her aldosterone was found to be 9682 pmol/L (normal <860 pmol/L) with renin ...

Alcohol use disorder is a prevalent and major but preventable cause of morbidity and mortality worldwide, causing several ...