In August of 2024, Brandon Aiyuk agreed to a four-year extension with the San Francisco 49ers worth $120 million, ($76 million fully guaranteed), making him one of the NFL’s highest-paid wide ...

The San Francisco 49ers caught the injury bug this past season, so they will be hoping the same does not happen in 2025.

The biggest beneficiary of an extended offseason for the San Francisco 49ers just might have been star running back Christian McCaffrey.

When it was announced on January 24, 2025 that the San Francisco 49ers were bringing Robert Saleh back to be their defensive coordinator once again, 49ers fans grew excited at the prospect of ...

After a four-year sentence in New York as head coach of the Jets, Robert Saleh returns to San Francisco as the defensive coordinator of the 49ers.

The San Francisco 49ers have announced they have signed DL C.J. West to a four-year deal.

The San Francisco 49ers have revamped their defense through the offseason with one of the new key components learning alongside star edge rusher Joey Bosa.

SANTA CLARA, Calif. (AP) — Mac Jones is happy finally to be with coach Kyle Shanahan and the San Francisco 49ers even if it came four years after many expected. Jones was linked to San Francisco ...

The Los Angeles Rams and San Francisco 49ers matchup is one of the top revenge games of the 2025 NFL season.

A huge tree toppled over in San Mateo Wednesday afternoon, crushing a number of cars and completely blocking a roadway.