The study suggests that autophagy stimulation may offer therapeutic benefits in the early stages of HD progression, with mTOR inhibition showing promise ... (2) For the general scientific community ...
Biological function and molecular mechanism of autophagy pathway. Autophagy has been initiated by the formation of pre-autophagosome structure via the action of several proteins. PI3K-AKT and ...
Total RNA was extracted using Trizol reagent (Thermo Fisher Scientific ... and the expression levels of mTOR and P62 were significantly increased, indicating that a high glucose environment would ...
A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ...
Rett syndrome is a rare genetic disease affecting 1 in 10,000 newborn girls, characterized by sudden regression around 1 year ...
Autophagy is the process by which cells digest and renew their internal structures, recycling damaged or malfunctioning ...
Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...
Headed by Drs. Antonio Zorzano and Saska Ivanova, a study published in the journal Autophagy unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing ...
Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...
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