The last NFL preseason game to kick off tonight is the San Francisco 49ers vs. the Denver Broncos in this rivalry matchup.

The San Francisco 49ers began their NFL preseason slate with an ugly 30-9 loss against the Denver Broncos in Santa Clara. The 49ers scored all nine points in the first quarter, but it was all Broncos ...

The San Francisco 49ers absorbed a 30-9 preseason loss to the Denver Broncos as No. 2 QB Mac Jones provided flashes of the frustration that has characterized his career.

Larger load expected vs. SF ...

No 49ers’ position group got more attention than the defensive line. Early indications are they found upgrades with Williams, ...

The San Francisco 49ers couldn't catch a break last season. Everything that could've gone wrong went wrong, and they're still ...

Kyle Shanhan revealed why standout 49ers rookie cornerback Upton Stout missed San Francisco's preseason opener against the ...

The San Francisco 49ers preseason game and the Golden State Valkyries game will be aired on KPIX 5 and on KPIX+ on Saturday.

The San Francisco 49ers opened their 2025 preseason slate at home, hosting the Denver Broncos at Levi's® Stadium. San ...

The Denver Broncos will take the field on Saturday night for their preseason opener against the San Francisco 49ers at Levi's ...

Jarrett Stidham threw two touchdown passes, leading the Denver Broncos to a 30-9 victory over the San Francisco 49ers. The ...

The San Francisco 49ers were blown out in their preseason opener, but Robert Saleh had the defense look good against Bo Nix.