We’ve put together a list of the best anti-wrinkle creams for smoothing out fine lines and reducing the appearance of ...

It blocks a protein that binds to a form of vitamin A (retinoic acid) in our cells, known as retinoic acid receptor alpha (RAR-α).

The best retinol for mature skin is one that pairs the ingredient with other anti-aging actives, like peptides, and isn’t too drying. Shop our top picks.