B cells found to be crucial for long-term vaccine protection, new study shows The new findings could help improve vaccine effectiveness in some immunocompromised patients Date: April 23, 2025 ...

B cell biohack: Immune cells to churn out custom antibodies 'We think we'll be able to completely customize everything about the antibody.' Date: July 22, 2024 Source: University of Southern ...

Key Findings from the RAG-17 IIT Study Presented at AAN 2025: The final data from the IIT (NCT05903690), a first-in-human, open-label, dose-escalation study involving six SOD1-ALS patients over ...

Clinical associations with B-ALL developmental states. Credit: Nature Cancer (2025). DOI: 10.1038/s43018-025-00987-2 ...

A “complete eradication” of B cells with chimeric antigen receptor T-cell therapy is responsible for the long-term, drug-free remission from autoimmune diseases observed after treatment ...

CAR T cells are genetically-altered cells that are designed to reset the immune system by targeting B cells, which are involved in the production of autoantibodies and lupus disease activity.

By removing such B cells, CAR-T therapy can stop disease progression or help reset the immune system. Though the therapy is approved only for cancer, research suggests that it could also help ...

"Historically, B cells have largely been ignored in the cancer research field, with scientists instead favoring research on 'killer' T cells," said co-lead author Allison Casey, Ph.D. candidate in ...

The study found that in the absence of B cells, CD8 T cells become overly active too early, burning out quickly and failing to develop into memory cells that provide long-term protection. This ...