Here, we describe the epidemiology of RSV, the RSV virion structure, key neutralizing epitopes on the pre- and post-fusion forms of the fusion protein and implications for vaccine development.

Vaccines against both viruses, however, have been difficult to design. Now, Scripps Research scientists have analyzed the ...

A new technique for studying the structure of the RSV virion and the activity of RSV in living cells could help researchers unlock the secrets of the virus, including how it enters cells, how it ...

A new technique for studying the structure of the RSV virion and the activity of RSV in living cells could help researchers unlock the secrets of the virus, including how it enters cells, how it ...

Figure 1. (Left) Pre- and (Right) Post-fusion forms of the RSV F protein. Protein structural arrangement occurs during the host-virus membrane fusion, signaling viral infection. 5 Image Credit ...

As the sole viral antigen on the HIV-1 virion surface, ... McLellan, J. S. et al. Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.

Updated 6:20 p.m. on Sept. 22, 2023 Every fall, when the air turns chilly and the leaves red, pediatric ICUs begin preparing for the onslaught of the virus known as RSV. Not flu, not COVID, but ...

RSV pre-F Protein: Innovative Tool for Structure-Based Vaccine Evaluation. Credit: ACRO Biosystems. Request For Info / Quote Advertisement. The trimeric pre-fusion glycoprotein F is essential for ...

Scientists have long known that an RSV protein, known as NS1, is behind the virus’ ability to evade the immune response, but the protein’s structure has been unknown until now.

Graham, who was leading RSV vaccine efforts there, learned that McLellan, who specialized in mapping the atomic structure of proteins, wanted to work on something “a little off the radar ...

Introduction; RSV virion & vaccine products; Epidemiology of RSV in children; Epidemiology of RSV in adults; Safety and efficacy of Nirsevimab in infants; Medical countermeasures ...