eLife

Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites

Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...
Technology Networks

An Introduction to Bioinformatics, Bioinformatics Tools and Applications

This article introduces the field of bioinformatics and its importance as a cornerstone of biological research, as well as ...
Technology Networks

Blood Test Could Detect Hidden Tuberculosis

Single-cell RNA sequencing identified distinct immune profiles in extrapulmonary TB, linking interferon–IL-1 signaling to ...
eLife

Cohesin reconstitution and homologous recombination repair of DNA double-strand breaks in late mitosis

The cohesin subunit Scc1 returns and reconstitutes the complex with Smc1–Smc3 in late mitosis upon DNA double-strand breaks, although it does not participate in homologous recombination-driven MAT ...