Additional research is necessary to demonstrate definitively the involvement of protein misfolding and aggregation as a common cause of neurodegenerative diseases. Future work should also focus on ...

Malaria remains a persistent public health burden, with Plasmodium falciparum causing the most dangerous form of malaria and ...

Misfolding of the prion protein triggers prion diseases such as Creutzfeldt-Jakob disease. All research findings to date indicate that the misfolded prion protein acquires toxic activity.

the scientists also uncovered new insights into the role of water around the protein surface that guides the misfolding process. A mutation commonly used to model tau-related diseases subtly ...

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell's main energy currency, ...

Tauopathies are neurodegenerative diseases driven by tau protein misfolding and subsequently accumulating into dense, ordered fibrils. These tauopathies are prion-like, meaning that misfolded tau ...

By developing investigational therapeutics targeting protein dysregulation in debilitating diseases such as Alzheimer’s and Parkinson's, the company has generated encouraging results from ...

Misfolding of the prion protein triggers prion diseases such as Creutzfeldt-Jakob disease. All research findings to date indicate that the misfolded prion protein acquires toxic activity.

the scientists also uncovered new insights into the role of water around the protein surface that guides the misfolding process. A mutation commonly used to model tau-related diseases subtly ...