“Previously Alzheimer’s research has been stuck looking at collateral damage in the form of misfolded, dead proteins that form plaques and tangles. Now it turns out that it is prion activity that ...

While there have been extensive studies of these plaques and tangles in the brains of people with Alzheimer’s, it can be challenging to discern which changes in the brain are from old age and which ...

Neuropathological examination during end-stage disease showed the deposition of prion protein in the form of frequent cortical amyloid plaques, cerebral amyloid angiopathy, and tauopathy.

Sponsor Message Strittmatter says there's no evidence the prion proteins fold into an abnormal shape or actually cause Alzheimer's. Instead, they seem to interact with early stage plaques in the ...

These plaques are a hallmark of the disease ... and it’s a familiar one – the prion protein. Incorrectly folded versions of this protein (PrPSC) are the culprits behind diseases like CJD ...

When prion proteins begin to fold abnormally and clump together — called amyloid plaques — it leads to brain damage. Disease-causing prions can transmit in various ways, for example ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The "mini prion" folds and stacks ...

Mark Zabel: Prion diseases belong to a larger family of diseases that we refer to as protein misfolding diseases. These are diseases that also are caused by normal proteins that we all express that ...

The National Prion Disease Pathology Surveillance Center (NPDPSC) is the only Center of its kind in the U.S., which coordinates autopsies and neuropathologic examinations of suspected prion disease ...

While there have been extensive studies of these plaques and tangles in the brains of people with Alzheimer’s, it can be challenging to discern which changes in the brain are from old age and which ...