Disease-associated prion protein (PrP Sc) accumulates in FDCs (ref. 6), which function as antibody- and complement-dependent antigen traps. Here we investigated whether the mechanisms by which ...

Figure 1: FACS analysis of spleen cells from BM-grafted uninfected mice, stained with PrP-specific antibody (open histograms) or unstained (shaded histograms). Figure 2: Confocal analysis of ...

May 28, 2025 — Researchers find high-fat diets set off metabolic dysfunction in cells, leading to weight gain, but these effects can be reversed by treatment with ... Researchers Engineer a ...

During atherosclerosis, lipid-rich plaques are formed in large- and medium-sized arteries, which can reduce blood flow to tissues. This situation becomes particularly precarious when a plaque develops ...

The goal of this study was to determine the prevalence of HRP in carotid arteries in Chinese patients with cerebral ischemic symptoms using standardized CMRI in a multicenter setting and characterize ...

Therefore, effective CVD interventions call for precise identification of the plaques to aid in clinical treatment of such diseases. Herein, a reactive oxygen species (ROS)-responsive sequentially ...