B shows a close up of a presynaptic bouton (cyan) and a postsynaptic spine (yellow). Red represents the synaptic contact plane of the pre and postsynaptic specializations. Normal synaptic structures ...

Accordingly, we performed a comprehensive 3D analysis of every excitatory presynaptic bouton, their embedded spinules, and postsynaptic densities, within a 5 nm isotropic FIB-SEM image volume from CA1 ...

A gaussian blur (sigma = 2 pixels, 154 nm) was used to smooth the signal and presynaptic terminals were scored subjectively, using the local intensity profile as a guide (further information below).

By varying the ratio between presynaptic olfactory PNs and postsynaptic KCs, we find that connectivity density is set by KCs: KC claw number changes little across a wide range of PN::KC ratios, KC ...

Seated next to him was another pitcher, Jim Bouton, famous for his tell-all book, “Ball Four.” Bouton was 36 and sticking around because he still loved baseball, even if it didn’t always ...

In control animals with normal visual experience, the formation of presynaptic boutons increased during the critical period and then declined. MD affected bouton formation, but with a delay, blocking ...

3) Localization of RPM-1 to presynaptic terminals early in development is consistent with delayed presynaptic bouton formation in rpm-1 mutants. rpm-1 mutants assemble synapses prior to synapse ...

Yet by recording from axons of cerebellar stellate cell (SC) interneurons, we show that AP width varies between presynaptic bouton sites, even within the same axon branch. The varicose geometry of SC ...