PCR, or Polymerase Chain Reaction, is a revolutionary molecular biology technique that allows for the rapid amplification of specific DNA sequences. It is an essential tool in various fields, ...

In a recent case presentation posted to the Research Square* preprint server, researchers reported on the misclassification of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron ...

Wheat (Triticum spp.) is often coinfected by several soil-borne fungal pathogens, causing serious crop yield and economic losses. Rapid diagnosis of infected fungi is critical for the application of ...

A polymerase chain reaction (PCR) test detects genetic material from a pathogen or abnormal cell sample. Ways of collecting samples include a nasal swab, a saliva swab, or taking a sample of blood.

Quantitative PCR (qPCR) instruments that operate in real-time need high sensitivity and the most favorable signal-to-noise ratio possible. The bandwidth of excitation, center wavelength (CWL) and ...

Microsatellite instability (MSI) arises from mismatch repair-deficiency (MMR-d) and is a predictor of immune checkpoint blockade (ICB) therapy response. Although MSI diagnostics typically yield a ...

This page from my notebook lists the chemicals which I put together into a single, purple-capped tube on September 8th, 1983, in a reaction I labeled PCR01. No cycling, only one tube, no variations, ...

When the first thermal cyclers for the polymerase chain reaction came out in the 1980s, they were as expensive as a market driven by grant money could make them. Things haven’t got much better over ...

Objectives: To determine the etiology of genital ulcer disease (GUD) among patients attending sexually transmitted disease (STD) clinics in Pune, India, and to examine the relationship to HIV ...