A painting by British artist George Stubbs is expected to sell for up to £2 million ($2.5 million) in London next week, as it comes to auction for the first time in more than 50 years.

History of the German Shorthaired Pointer. This dog breed’s name is a clear giveaway to its country of origin. The German shorthaired pointer did, in fact, originate in Germany in the 1800s.

The 18th century artwork of a Spanish pointer dog was last on the market in 1972 when it sold for £30,000 ($37,700), according to Sotheby’s, which is handling the sale. It was first auctioned ...