Current understanding of microvascular changes in chronic limb-threatening ischemia remains limited, partly because the tissue microvasculature is difficult to study in human patients.

Acute limb ischemia occurs due to a sudden decrease in the blood flow to a limb, resulting in a potential threat to the viability of the extremity. Unfortunately, the threat is not only to the ...

Acute limb ischemia (ALI) results from a sudden obstruction in the arterial flow to the extremity due to an embolism or thrombosis. Embolic problems result in a greater degree of ischemia than ...

Burke Neurological Institute, White Plains, NY (H.J., I.P., K.W.P., J.M., A.M., S.C.). InVitro Cell Research, Englewood, NJ (H.J., J.W.C.). Helen & Robert Appel ...

Methods: The therapeutic benefits of recombinant GDF11 (rGDF11) were evaluated using a rat ischemic stroke model, in which focal cerebral infarcts were induced in 8 –10 week-old young adult male ...

Background: Magnetic resonance diffusion-weighted imaging (DWI) is the most sensitive modality for ischemic stroke diagnosis. However, DWI may fail to detect ischemic lesions in a proportion of ...

Cerebral ischemia and the subsequent cerebral ischemia-reperfusion (I/R) injury usually result in neuronal impairment with serious disabilities. Although neural stem cell (NSC) transplantation can ...

Correspondence to Dr Thomas Joseph Ford, BHF Cardiovascular Research Centre, University of Glasgow College of Medical Veterinary and Life Sciences, Glasgow G128QQ, UK; tom.ford{at}health.nsw.gov.au ...

Correspondence to Dr Karol P Budohoski, Division of Neurosurgery, Addenbrooke's Hospital, Hills Road, Box 167, Cambridge CB2 0QQ, UK; karol.budohoski{at}gmail.com Cerebral vasospasm has traditionally ...