In 2022, there were about 1.25 billion tobacco users ages 15 and older, down from 1.36 billion in 2000. But countries around the world had set a bigger goal.

“I like it better than chewing tobacco,” Whalen said. “The thought of chewing grosses me out.” He now wants to quit Zyn, however, because nicotine is causing him anxiety. But it’s highly ...