Ketosis is a significant metabolic disorder caused by negative energy balance (NEB). β-hydroxybutyrate (BHBA) is the most abundant circulating ketone body and is known to accumulate within follicular ...

EGR1 expression was significantly reduced in SR48692-treated cells and was found to be essential for oocyte maturation. The ERK1/2 pathway, known to activate EGR1, was inhibited by SR48692 ...

A new research paper was published in Aging (Aging-US) on February 18, 2025, Volume 17, Issue 2, titled "Transcriptomic landscape of cumulus cells from patients <38 years old with a history of ...

Wyse, B.A., Fuchs Weizman, N., Kadish, S., Balakier, H., Sangaralingam, M. and Librach, C.L. (2020) Transcriptomics of Cumulus Cells—A Window into Oocyte Maturation in Humans. Journal of ...

Oocytes from which the cumulus granulosa cells have been removed (denuded) will mature in vitro in the absence of LH or EGF. Since the effect of the inhibitors is to break the contact between the ...

The ATP level of all mice cumulus cells obtained was measured. The results of thet-test on ATP level of the two groups showed a significant difference (p < 0.05) with ATP level of the control group ...

As the time of ovulation draws near, mouse spermatozoa move out of the isthmic reservoir, which is a prerequisite for fertilization. However, the molecular mechanism remains unclear. The present study ...

Somatic cells — not just sperm or eggs — can be used to clone healthy mice, even after being freeze-dried and stored for up to nine months.