The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating ...

Scientists have discovered that rhythmic oscillations of a specific neurotransmitter play a vital role in clearing toxic proteins from the brain during non-rapid eye movement (non-REM) sleep. These ...

They found that as levels of a molecule called norepinephrine (also called noradrenaline) rise, blood vessels in the brain constrict, decreasing the volume of blood and allowing cerebrospinal ...

Norepinephrine triggers blood vessels to contract ... This oscillation, in turn, generates the pumping action necessary to move CSF in the glymphatic system during sleep.

Treatments with High dose psychostimulants that block DAT as well as the norepinephrine (NET) and serotonin (SERT) transporters (60 mg/kg cocaine or methylphenidate) significantly impaired PPI ...

Her study found the glymphatic clearance was mediated by a hormone called norepinephrine and happened almost exclusively during the NREM sleep phase. But it only worked when sleep was natural.

What is norepinephrine, if one asks? They regulate energy levels, stress responses and alertness. This dual action can result in additional benefits like increased energy, reduced chronic pain ...

This important study provides new evidence on the role of norepinephrine (NE) release in the hippocampus in response to environmental transitions (event boundaries), providing a potential link between ...

Ephedrine sulfate is a sympathomimetic amine that directly acts as an agonist at α-and ß-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons.