According to the World Health Organization (WHO), over 22% of the global population smokes, with more than 9 million smoking-related deaths reported annually. Effective treatments to alleviate ...

Introduction: The cholinergic anti-inflammatory pathway regulates immune responses through the alpha7 nicotinic acetylcholine receptor (α7nAChR), found in neurons, macrophages, and monocytes. α7nAChR ...

Department of Pharmaceutical Sciences, Medicinal Chemistry Section “Pietro Pratesi”, University of Milan, Via L. Mangiagalli 25, Milan 20133, Italy ...

A recent case report by Sahota and colleagues has provided new insights into treatment of dysglycemia via dopamine (DA) receptor stimulation in the setting of autoimmune diabetes (1). Briefly, a ...

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The delta opioid receptor (DOP) plays a key role in mood ... However, the precise molecular mechanisms underlying their actions remain unclear. Understanding the neurological mechanisms that ...

A novel technique to identify and locate lipids in the brain The research group was able to understand the mechanism ... cannabinoid receptors were seen to be activated and the acetylcholine ...

Myasthenia Gravis (MG) is a common neuromuscular junction disorder that is primarily mediated by anti-acetylcholine receptor antibodies (AChR-Ab). However, using AChR-Ab titers to predict MG severity ...

Perhaps surprisingly for such a fundamental physiological mechanism, there is little or no redundancy in the components of the axis. There is only a single POMC gene, a single specific receptor ...