This research will provide valuable insights into our understanding of mechanisms of addiction ... with the upregulation of nicotinic acetylcholine receptors (nAChRs), a critical indicator of ...

The Vivacity-MG3 study is currently in its open-label extension phase, which is investigating the longer-term safety and ...

The discovery and development of GLP-1 receptor agonists for type 2 diabetes and obesity is a bench-to-bedside success story.1 Multiple GLP-1 receptor agonists are now in clinical use, such as ...

In preliminary studies, we discovered that selected typical and atypical antipsychotic drugs interacted with virtually every biogenic amine receptor tested, in confirmation of many prior studies ...

M2 receptors, located on the postganglion endings of the cholinergic fibers, with the role of limiting further acetylcholine release from the postganglion endings; and M3 receptors, located on the ...

Moreover, we synopsize the regulatory mechanisms within the liver under diverse pathological ... PCSK9, Proprotein Convertase Subtilisin/Kexin 9; LDLR, low density lipoprotein receptor; FPN, ...

A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites, also known as natural products. Natural products have been a prolific source and an inspiration for numerous ...

Expert Rev Endocrinol Metab. 2010;5(5):653-662.

Department of Pharmacology and Computational Medicine Program, University of North Carolina−Chapel Hill, Chapel Hill, North Carolina 27599, United States ...

Department of Biophysics, Graduate School of Science, Kyoto University, Kyoto, Japan ...