The brain really is an incredible organ, and neurons are the vital link between, well, everything. The brain is anything but set in stone; how we think, feel, reason, and understand the world changes ...

Experiences cause the strength of these connections to change—a process called synaptic plasticity, which underlies learning and memory. But exactly where in the brain these changes occur during the ...

Neuronal plasticity is a fundamental process in neuronal development and recovery from brain disorders. The Trophin lab focuses on the role of neurotrophic factors, particularly Brain-Derived ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

Synaptic plasticity is the basis of information storage ... Moreover, this mobility can be driven by neuronal activity through several signals. Many proteins and signalling mechanisms have been ...

Instead, they saw that the activity was slightly different every time, and reasoned that these changes reflected synaptic plasticity. To understand what drives these constant changes in neuronal ...

In 1898, Camillo Golgi, an eminent Italian physician and pathologist, published a landmark paper on the structure of “nervous cells.” In addition to the organelle that still bears his name, the Golgi ...

The cells with electrophysiological activity obtained at the University of the Basque Country (UPV/EHU) are opening up new avenues for the study of neurodegenerative diseases and the development of ...

He went on to show that neuronal activity drives Fos expression, kickstarting the production of synaptic plasticity-related genes and leading to long-term changes in connectivity. Fos acts on ...

COX-2 is involved in prostaglandin synthesis and expressed throughout the nervous system, where it participates in pain sensitivity and in synaptic plasticity. Microsomal prostaglandin E synthase ...

Furthermore, this study demonstrates that the reorganization of sensory maps does not rely on neuronal activity in ... its crucial role in brain plasticity and the reorganization of tactile ...