This useful study presents a biologically realistic, large-scale cortical model of the rat's non-barrel somatosensory cortex, investigating synaptic plasticity of excitatory connections under varying ...

How do animals bounce back from sleep deprivation? Scientists found a subset of neurons in the mouse thalamus that repay this ...

Semaglutide, a synthetic analog of glucagon-like peptide-1 (GLP-1), has garnered attention for its intriguing properties and potential implications in various r ...

Homeostatic plasticity maintains normal brain functions by constraining various network features of neural circuits, yet how this is realized on the cellular level remains unknown. Synaptic and ...

About This reporsitory hosts simulation files, data and plotting notebooks supporting the preprint 'Repetitive transcranial magnetic stimulation (rTMS) triggers dose-dependent homeostatic rewiring in ...

Hebbian plasticity and homeostatic plasticity are the two major forms of activity-dependent plasticity that modify neuronal circuits (Turrigiano, 2008). Hebbian plasticity refers to plasticity that ...

The team suggests that rapid synaptic scaling, an important mechanism in homeostatic plasticity, is something that must occur in order for rapid antidepressant action to occur.

Homeostatic plasticity refers to the capacity of neurons to regulate their own excitability relative to the activity of the larger networks which they, in large numbers, form. It is one of several ...

Tingting Wang, an assistant professor in the department of pharmacology and principal investigator of the Wang Lab, uses techniques like gene editing and computational modeling to understand how ...