Specifically, the topic seeks contributions that discuss: - The biology and pathophysiology of complement-mediated GN. - Emerging therapeutic agents targeting the complement cascade (e.g., factor ...

The US regulator has started a review of Roche's supplemental biologics license application (BLA) for Gazyva/Gazyvaro (obinutuzumab) as a treatment for lupus nephritis, with a decision expected in ...

Aurinia Pharma and partner Otsuka have secured approval in the EU for Lupkynis, billed as the first oral treatment for active nephritis in patients with the autoimmune disease systemic lupus ...

In the following two articles, the pathophysiology, medical management, and nursing care of patients are discussed. An in-depth model care plan illustrates the complexity of the disease and its ...

Between 30% to 50% of those diagnosed with lupus will develop kidney disease, also known as lupus nephritis, within the first six months to three years of their condition. In people with lupus, the ...

Functional dyspepsia is a symptom complex characterised by postprandial upper abdominal discomfort or pain, early satiety, nausea, vomiting, abdominal distension, bloating, and anorexia in the absence ...

In most cases, it does not cause renal injury. A case of K. equi-associated granulomatous nephritis leading to uremia in a brazilian mare is described. The animal presented colic, and among the ...

Background Long-term immunosuppressive treatment does not efficiently prevent relapses of lupus nephritis (LN). This investigator-initiated randomised trial tested whether mycophenolate mofetil (MMF) ...

Despite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become a global health concern. The disease affects approximately ...

Dr Martin Riedel, Deutsches Herzzentrum und I. Medizinische Klinik, Technische Universität München, Lazarettstr. 36, D-80636 München, Germanym.riedel{at}dhm.mhn.de If you wish to reuse any or all of ...

After a full examination that involved a discussion of symptoms and blood and imaging tests, Alicia was diagnosed with multi-organ-involvement lupus with lupus nephritis. This case illustrates how ...