NEW ORLEANS, LA — A long-awaited trial suggests the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib has similar cardiovascular safety as naproxen and ibuprofen in arthritis patients at ...

Aleve’s recommended dosage is every 12 hours. According to ClinCalc.com, naproxen was the 93rd most-prescribed medication in the U.S. in 2021 with 7.6 million prescriptions.

Ibuprofen, by comparison, works faster than naproxen. However, because ibuprofen’s effects wear off quicker, it needs to be taken more frequently throughout the day, she says.

Ibuprofen (Advil or Motrin), naproxen (Aleve) and aspirin (Bayer or Ecotrin) are common pain relievers that belong to a class of medication called non-steroidal anti-inflammatory drugs (NSAIDs).

Where the Naproxen Story Went Wrong When NIH Halted a Major Study, Citing Risks From a Common Painkiller, the Media Played the News Big. That Was Just Part of the Problem ...