Ideally, eye swaps could potentially save the clan from the debilitating effects of strain and even blindness. But the reason why it wouldn’t work was because of the rarity of the Mangekyou Sharingan.

The manga's previous chapter saw Sarada Uchiha use her Mangekyo Sharingan ability Ohirume against Ryu. While Ryu tried countering it, Ohirume sucked Ryu towards one of its black spheres and exploded.