AFC meets NFC in an in-state 2025 NFL preseason battle as the Buffalo Bills host the New York Giants on Saturday. The Bills topped the AFC East last season with a 13-4 record, and are looking to have another strong season before making a deeper playoff run.

It will be the last first preseason game at Highmark Stadium when the Bills take on the New York Giants. It’s also going to be amid afternoon summer heat, with a 1 p.m. kickoff and highs in the upper 80s.

The New York Giants and the Buffalo Bills will kick off their 2025 preseason at Highmark Stadium on Saturday. The wait is finally over as the NFL preseason is officially here, and these two squads continue their preparation for their opening games of the regular season during this matchup.