Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear ...

When interleukin-12 is added to the cell culture, it leads to a significant reduction in nerve fibers (pink) and oligodendrocytes, and thus to a decline in myelin (white).

Researchers from Charité – Universitätsmedizin Berlin and the Max Delbrück Center have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer's ...