Heroin activates a protein found in the brain, spinal cord and gastrointestinal tract called the mu opioid receptor. When activated ... would go to the pharmacist and get a daily dose of methadone or ...

Opioids are integral to analgesic protocols due to their high potency and efficacy in treating different pain in human and veterinary medicine. Injectable µ-receptor opioid agonists such as morphine, ...

This medicine may be one of the best tools doctors have to fight the fentanyl crisis. Preparation of a dose of Buprenorphine, ...

New research suggests that δ-receptor agonists regulate intestinal motility and relieve abdominal pain in a mouse model of irritable bowel syndrome, potentially offering a novel CNS-targeted ...

A drug called buprenorphine may be the best tool doctors have to fight the fentanyl crisis. Why hasn’t it been more widely ...

The use of non-medical opioids has reached 60 million in 2021. Methadone-assisted treatment (MAT) is a widely used harm-reduction strategy for opioid addiction. However, methadone can cause cognitive ...

A study showed that changes in the functioning of opioid neurotransmitters in the brain may underlie anorexia. A study conducted at Turku PET Centre in Finland showed that changes in the ...

Having shown last week that its opioid alternative can reduce post-surgery pain, Tris Pharma is back with another slice of clinical data to show that the drug is less likely to be abused.

The company tested cebranopadol, a dual nociceptin/orphanin FQ peptide (NOP) receptor and µ-opioid peptide (MOP) receptor agonist, in a late-stage trial on patients who have undergone cosmetic ...

From 2011 to 2021, prescription opioid use dropped by about 50% across the United States as a likely sign of attempts to reduce overuse of the drugs, previous studies found.

Attempting to reduce fatal opioid overdoses and encourage more people to seek treatment, fire department paramedics in Kitsap County will start administering the medication buprenorphine in the ...