The study, “ Anorexia nervosa is associated with higher brain mu-opioid receptor availability,” was authored by Kyoungjune Pak, Jouni Tuisku, Henry K. Karlsson, Jussi Hirvonen, Eleni Rebelos ...

7-hydroxymitragynine (7OH) is a naturally occurring alkaloid found in the kratom plant (Mitragyna speciosa). As a partial agonist of the mu-opioid receptor, 7OH produces a range of effects ...

It acts as a partial agonist at the mu-opioid receptor, and its pharmacological activity has made it a focal point for research on non-traditional alternatives to opioid analgesics.

Blocking opioid receptors outside the brain reverses opioid overdose without sudden and severe withdrawal symptoms. Credit: eLife (2025). DOI: 10.7554/eLife.104469.3 ...

The mu-opioid receptor system, which normally encourages eating by making food feel pleasurable, may function differently in these individuals. Higher receptor availability could reflect an attempt by ...

Purdue Pharma’s $7B Opioid Settlement Could Advance Soon After States Back It OxyContin maker Purdue Pharma ’s latest plan to settle thousands of lawsuits over the toll of opioids could soon ...

Tris Pharma has set its sights on an FDA filing for pipeline drug cebranopadol before the end of this year after the drug achieved significant pain relief in abdominoplasty patients in a late ...

Judge could advance Purdue Pharma's $7B opioid settlement after all 50 states back it If approved, the settlement would be among the largest in a wave of lawsuits over the past decade.

Novel therapeutic strategies, including biased MOR agonists, opioid vaccines, and splice variant-specific agonists, offer promise for safer pain management and reduced abuse liability. However, a ...

Nasdaq Listed Nasdaq 100 Alerts Market: Open Micron Technology, Inc. Common Stock (MU) Bid: $127.34 X 427 Ask: $127.36 X 600 Volume: 14,151,693 ...

After years in development, the FDA has started its review of Pfizer and Eli Lilly’s new painkiller tanezumab, one of two remaining drugs in the ill-fated nerve growth factor (NGF) inhibitor ...

A deadly synthetic opioid named Nitazene is sending London clubland into a panic as two more were killed by the drug. The drugs, believed to be up to 500 times stronger than heroin, is said to be ...