Ever since Biogen and Eisai’s Aduhelm (aducanemab) was approved in 2021 as the first antibody to treat Alzheimer’s disease by ...

BEIJING--(BUSINESS WIRE)--Biocytogen Pharmaceuticals (Beijing) Co., Ltd. ("Biocytogen", HKEX: 02315) today officially launched its fully human heavy chain antibody platform, RenNano™. RenNano ...

Affinity of antibody before and after humanization Before humanization, mouse antibody KD=6.38E-12M. Image Credit: Sino Biological After humanization, humanized antibody KD=3.90E-12M.

Set to become the leading platform for human antibody generation, the innovative RenMab™ mouse model utilizes chromosome engineering to remove the entire mouse immunoglobin (Ig) heavy chain ...

As a result, the entire mouse antibody heavy chain VDJ region is replaced with its full human heavy chain VDJ counterpart (123-129V, 27D, and 9J), along with the entire mouse kappa light chain VJ ...

Leveraging the RenMice platform, the RenBiologics™ program has generated over 1,000,000 fully human antibody sequences and numerous high-potential preclinical candidates against more than 1,000 ...