Anti-CD20 mAbs were originally created to treat B cell proliferative diseases such as non-Hodgkin's lymphoma and chronic ...

Monoclonal antibodies are novel therapeutic ... their efficacy and between the agents themselves. Antibodies against B cells Rituximab is a depleting antibody directed against CD20 on the surface ...

Mantle cell lymphoma (MCL) is an uncommon subtype of B-cell lymphomathat is characterized by monoclonal B cells that express CD5 on their surface, but not CD23, and harbor the t(11:14) chromosomal ...

If policymakers fail to act swiftly to restore medical research funding, then it’s up to those of us in the industry with the ...

Scientists create monoclonal antibodies by cloning a single antibody-producing cell line. In contrast to polyclonal antibodies, monoclonals are highly specific to an antigen. By fusing myeloma cells ...

(Reuters) - A newly discovered bat coronavirus uses the same cell-surface protein to gain entry into human cells as the ...

Laura is an assistant editor for The Scientist. She earned her PhD in biomedical sciences from Rush University by studying how circadian rhythms and alcohol affect the gut. View Full Profile. Learn ...

The first generation of mAbs, unveiled in 1975 (ref. 1), were murine mAbs derived from mouse B-cell hybridomas (see “Monoclonal antibodies by design”). However, as murine mAbs moved into ...

Scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood -- known as the tertiary lymphoid structure -- where they become ...

Nona Biosciences, a global biotechnology company providing a total solution from "Idea to IND" (I to I™), today announced a ...

Recently approved treatments for generalized myasthenia gravis (gMG), including complement and neonatal Fc receptor (FcRn) ...

Monoclonal gammopathy of undetermined significance (MGUS ... Like multiple myeloma, MGUS starts in a type of white blood cell called plasma cells. These cells make m-protein. This abnormal protein can ...