Telomere damage drives T cell exhaustion. Antioxidants restored their cancer-fighting strength in mice. Tumor environments place heavy stress on immune cells that fight cancer. Limited oxygen, ...

Scientists have just taken the most detailed look yet at the biology of a record-breaking human life, profiling a woman who ...

VIB researchers and colleagues have discovered a mechanism through which melanoma cells adapt and switch between two major ...

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have ...

Diffuse midline glioma, a type of rare and often fatal brain cancer, affects 2,000 children and young adults in the United ...

New research published in Immunity by researchers at the University of Pittsburgh found that, in mice, the toxic tumor environment causes mitochondria to generate reactive oxygen species (ROS) that ...

The FDA said it is going to label leucovorin for treating autism, but some scientists said more evidence of the drug's safety and efficacy was needed.

Samples from Spanish supercentenarian María Branyas Morera reveal the keys to her exceptional genetics and provide clues for ...

Scientists have discovered stress-sensitive proteins In skin biopsy-derived cells that could act as biomarkers for ...