To investigate how plants control endosymbiotic gene transfer, the team focused on the repair pathways for double-strand breaks — known entry points for organellar DNA. Using genetically engineered ...

More information: F. Li et al, Structural and molecular basis of PCNA-activated FAN1 nuclease function in DNA repair, Nature Communications (2025). DOI: 10.1038/s41467-025-59323-y ...

The team had previously found that LEM-3 plays a critical role in resolving persistent DNA bridges, acting as a last resort when other repair pathways fail. LEM-3 was specifically observed to ...

There is a simple discount patient access scheme for nivolumab, and a patient access scheme plus commercial access agreement for ipilimumab. NHS organisations can get details on the Commercial Access ...

There is a simple discount patient access scheme for dostarlimab. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS organisations can contact UK.pas@gsk.com ...

DNA analysis has revealed that 26 novel species of "extremophile" bacteria were lurking in a clean room that housed NASA's Phoenix lander before it was launched to Mars in 2007. The hardy microbes ...

The work will be of interest to the community of homologous recombination and DNA repair, as well as genome stability more ... the complementary sequence of the donor DNA was incorporated in a 10-nt ...