A study was made of the effects of 6-mercaptopurine (6-MP) upon nucleic acid metabolism in L1210 leukemia cells in vitro. Pharmacological concentrations of 6-MP inhibited the incorporation of both ...

Feb. 11, 2025 — A complementary drug to combat Alzheimer's disease could target a specific part of the nerve cell protein tau. This is the finding of new research which also offers a better way ...

Pharmacology is a branch of biomedical science, encompassing clinical pharmacology, that is concerned with the effects of drugs/pharmaceuticals and other xenobiotics on living systems, as well as ...

Clinical pharmacology is a branch of biomedical science. It includes drug discovery, the study of the effects of drugs on their targets in living systems and their clinical use, as well as the ...

Therapy was initiated with antibiotics, steroids and 6-mercaptopurine, on which the white-cell count rose to 170,000. The patient was placed in a croupette, and nitrous oxide administration was ...

I am a 67-year-old male with generally good vision. I have had a few floaters in my eyes over the years, but they have generally been small ...

BACKGROUND: 6-Mercaptopurine and its prodrug azathioprine are effective medications for refractory inflammatory bowel disease. However, use of these drugs has been limited by concerns about their ...

Learning and studying pharmacology – drugs, indications, mechanisms of action, contraindications and more – is one of the most difficult aspects of paramedic training. On Facebook we asked for ...

The Department of Biochemistry and Molecular Pharmacology at NYU Langone Health has a rich and distinguished history and maintains active research programs in epigenetics, genome integrity, protein ...

Many drugs are being administered to tackle coronavirus disease 2019 (COVID-19) pandemic situations without establishing clinical effectiveness or tailoring safety. A repurposing strategy might be ...

Applicants to the Ph.D. program Concentrations in Medicinal Chemistry, Pharmaceutics and Pharmacology must have, or nearly have, at least a Bachelor’s degree in pharmacy, biology, biochemistry, ...

Background: Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is associated with high rates of treatment failure and poor outcome. Activation of ABL/Src family kinases is found ...