ANSWER: Pernicious anemia (PA) is an autoimmune disease where the body destroys the cells in the stomach that make intrinsic factor (IF) -- a glycoprotein needed for the efficient absorption of B12.

Macrocytic and Megaloblastic Anemia When the body is deficient in vitamin B-12. it can produce red blood cells that are abnormally large, called macrocytes, which do not function properly.

A comprehensive discussion of megaloblastic anemia of infancy by Zuelzer and Rutzky 4 included the notation of a five-month-old breast-fed infant with megaloblastic anemia who responded to vitamin ...

Archive Megaloblastic Anemia of Infancy Secondary to Maternal Pernicious Anemia Authors: Beatrice C. Lampkin, M.D., Nomie A. Shore, M.D., and David Chadwick, M.D. Author Info & Affiliations ...