We had previously suggested that a threshold level of mast cell content (tryptase, chymase and so on) exists [15] above which it can provoke coronary artery spasm and/or plaque erosion or rupture.

Trypsin and mast cell tryptase cleave proteinase-activated receptor 2 and, by unknown mechanisms, induce widespread inflammation. We found that a large proportion of primary spinal afferent ...

Gayathiri Jeyatheesan, 28, died at Aintree University Hospital on January 25 this year, shortly after eating crab meat. The ...

Onyinye I. Iweala discusses a recently published review that provided updated recommendations for ordering tryptase tests, sharing her expert insights. State‑of‑the‑art recommendations for clinician ...

Allergen-specific antibody test, basophil activation assay, measurement of inflammatory mediators released, (i.e., mast cell tryptase) and lymphocyte stimulation studies are other tests used as ...

Learn all about anaphylaxis, its symptoms, causes, and treatment. Recognise signs early and act quickly to manage this severe ...

Lower tryptase levels after 18 hours were reported in other events that occurred in the same individual and thus might reflect “a partial depletion of mast cell tryptase stores in this . . . patient ...

Tryptase genotyping is required when assessing patients for the WHO minor criterion, BST > 20 ng/ml, especially in those with monoclonal mast cell activation syndrome, bone marrow mastocytosis (BMM), ...

Background Mast cell activation is thought to be involved in visceral hypersensitivity ... In addition, mast cells were quantified and spontaneous release of tryptase and histamine was determined in ...

Primary endpoint is reduction in peak esophageal epithelial mast cell count (PMC) cell at 12 weeks ... Intraepithelial mast cells (Tryptase and CD117 positive) and eosinophil counts per hpf from ...