Here, we show that accumulation of mutations in a drug-resistant HIV-1 protease (HIV-1 PR) variant, D30N/M36I/A71V, changes the fractional occupancy of the equilibrium conformational sampling ensemble ...

Mycoplasmas are considered the smallest cells capable of propagation in cell-free medium, and some species are pathogenic ... the peptide/opine/nickel uptake transporter family (3.A.1.5.1), is ...

In this report we explore the use of MALDI-FTICR mass spectrometry for the quantitative analysis of five HIV-1 protease inhibitors in cell lysates. 2,5-Dihydroxybenzoic acid (DHB) was used as the ...

Here, we show that forcing a metabolic change in embryonic stem cells (ESCs) promotes a developmental identity that better approximates the inner cell mass (ICM) of the early mammalian blastocyst in ...

People often refer to mitochondria as the powerhouses of the cell. Their main function is to generate the energy necessary to power cells, but they are also involved in cell signaling and death.

which activate platelets and induce protease-activated receptor (PAR)–mediated signaling, with release of more inflammatory cytokines, upregulation of leukocyte adhesion molecules (intercellular ...

KOTA KINABALU: Sabah state flags will be flown at half-mast on Wednesday (May 21 ... He was sworn in as the Sabah Governor on January 1, 2003, and served two terms until December 31, 2010.

A bill passed this week by the Missouri legislature would mandate a near complete ban of cell phone use in public schools during the school day, including during lunch and free periods ...

PORTLAND, Ore. — Oregon Gov. Tina Kotek has ordered flags to be flown at half-staff at public institutions across the state on Thursday. The governor issued the proclamation in honor of Peace ...

The last known surviving Second World War veteran of a Hamilton-based regiment turns 104 Friday. Tony Mastromatteo, now an honorary lance corporal with The Argyll and Sutherland Highlanders of ...