These cells were found to promote airway inflammation through the characteristic effector molecule Granzyme K (GZMK), which is a serine protease involved in inflammatory pathway activation.

A major initiator of pemphigoid diseases is the accumulation of autoantibodies against proteins at the dermal-epidermal junction (DEJ), followed by protease activation at ... passive-transfer disease ...

The numbers of mast cells per 1 mm 2 in jejunum or skin sections were determined. After aseptic removal of jejunum, homogenate was prepared. Lysis solution with 1% TRITON-X (Sigma-Aldrich, USA) and ...

SARS-CoV-2 enters host cells via cell receptor ACE II (ACE2) and the transmembrane serine protease 2 (TMPRSS2 ... data expression matrix was processed with the R package Seurat (V.3.1.4).19 We first ...

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, ...

Food allergies can be life-threatening due to the rapid and exaggerated immune response. While mucosal mast cells (MMCs) are ...

Mast Capital and Starwood Capital Group secured construction financing for their oceanfront luxury condo project in Miami Beach. The joint venture closed on a $390 million loan from Eldridge ...

WHILE examining the histology of tuberculoid and lepromatous skin lesions of leprosy, we noted that there were many cells containing acid-fast granules in the cytoplasm, around the granulomatous ...

A $1 billion arms sale package to Israel was paused ... House Foreign Affairs Committee Chairman Brian Mast (R-FL) told the Washington Examiner that ranking member Gregory Meeks (D-NY) paused ...

Factors induced during stress in the brain and/or skin, such as corticotropin-releasing hormone, neuropeptides, neurotrophins and α-melanocyte-stimulating hormone, can activate mast cells to ...