Mast cell activation syndrome is a condition that causes mast cells to release an inappropriate amount of chemicals into your body. This causes allergy symptoms and a wide range of other symptoms ...

Mast cells contain granules packed with over 200 signaling chemicals including histamine, prostaglandins, leukotrienes and cytokines. When functioning properly, they release these substances in ...

Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an ...

Mast cell tumors appear on cats as small, firm, hairless raised bumps or lumps on the skin. Your cat may or may not have some itching in those areas, depending on how it reacts to histamine ...

Jeff Hersh, Ph.D., M.D., can be reached at DrHersh@juno.com. This article originally appeared on MetroWest Daily News: Dr. Hersh: Mast cell activation syndrome can cause numerous symptoms ...

Thus, mast-cell-specific MrgprB2 likely plays a role in mediating behaviors linked to alcohol-withdrawal-induced headaches. The researchers also assessed the effects of ethanol withdrawal on TG ...

Mast cell leukemia is a subtype of mastocytosis. It is extremely rare but very aggressive. Due to its rarity, there are few clinical trials on this condition.

Chymase from mast cells was present at high levels in the sera of these patients, further proof of mast cell activation in COVID-19. Thus, SARS-CoV-2 causes mast cell activation in vivo.

According to a recent review, data suggest mast cells have an important role in tissue homeostasis and wound healing, with mass cell dysregulation potentially leading to fibrotic disease.

Targeting KIT by frameshifting mRNA transcripts as a therapeutic strategy for aggressive mast cell neoplasms. Molecular Therapy, 2021; DOI: 10.1016/j.ymthe.2021.08.009 ...

A potential new treatment for mast cell cancers reduces the number of mast cells by “mutating” the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene ...