This is a well-written study that presents a solid genetic screen to identify regulators of adipose morphology and remodeling in zebrafish. The authors generated a rigorous screening platform based on ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Hoth Therapeutics Secures Japanese Patent for Breakthrough HT-KIT Platform Targeting Mast Cell Diseases Provided by PR Newswire Jun 12, 2025, 6:17:00 AM ...

Discover 8 ways mast cell activation syndrome causes widespread symptoms from digestive issues to brain fog, often mistaken for other conditions.

Rep. Brian Mast, a Florida Republican, wore an Israeli army uniform when he arrived for a House Republicans' caucus meeting at the U.S. Capitol complex, Oct. 13, 2023. His shoulder patch ...

Ultimately, her research led to mast cell activation syndrome, or MCAS, a condition in which mast cells (a type of white blood cell) overreact for reasons that aren’t always clear.

Mast cell activation syndrome (MCAS) is a condition where the mast cells are inappropriately triggered.

Mast cell activation syndrome (MCAS) is a condition where the mast cells are inappropriately triggered.

Immune cell trapping during allergic responses Mast cells, residing in tissues and critical for initiating inflammation, are filled with granules containing pro-inflammatory substances.

Background: Mast Cell Leukemia (MCL) is one of the rarest encountered malignancies. It is an aggressive oncologic subtype of systemic mastocytosis (SM) and accounts for <1% of total cases. To make the ...

Mast Cell Activation Syndrome (MCAS) results in repeated, severe allergy symptoms affecting the entire body, including skin, gastrointestinal tract, heart, respiratory, and neurologic systems.