At six months, women had lost an average of 10.8kg of fat mass, but only 1.4 pounds of muscle mass (0.63kg), while men had lost 25 pounds of fat mass (12kg) and only 2.4 pounds of muscle mass (1kg).

NATIONAL HARBOR, Md. — GLP-1 receptor agonists are effective weight-loss medications, but they may also decrease muscle mass, raising concerns about the long-term effects of these drugs ...

In a Phase 2 trial, patients taking the highest-dose combination of Wegovy and the drug, called bimagrumab, lost 22% of their weight at 72 weeks. Ninety-three percent of that was fat mass, and the ...