The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism.

The result suggests that the protein made by the gene, known as Nwd1, and other molecules it interacts with could be worthwhile targets for new MASH therapies. The scientists published their work ...

Katy Perry stopped by The Morning Mash Up at SiriusXM Studios in Las Vegas on Thursday to promote her upcoming "The Lifetimes Tour," which kicks off in Mexico City on April 23. The "Roar" hitmaker ...

Today, MASH remains a complicated disease ... Other research in animal models has demonstrated the capacity for FGF21 to counteract hyperglycemia, diet-related obesity, hyperlipidemia, and ...

These computational models simulate biological processes to ... we are especially focused on fibrotic liver disease (such as MASH), whilst our ADME applications look at metabolism, absorption ...

Moreover, researchers found that PPP6C expression levels were significantly reduced in liver tissues from both clinical patients and mouse models of MASH, indicating that PPP6C may act as a ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions ...

The results are consistent with icosabutate’s anti-fibrotic effects in pre-clinical models and anti-proliferative ... in fibrosis without worsening of MASH versus 9.6% of placebo treated ...