Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

NF1 drug development accelerates with novel treatments aiming to surpass current MEK inhibitors in efficacy, safety, and patient-friendly delivery. The evolving NF1 landscape highlights how innovation ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Results The task force agreed on 5 overarching principles and 11 recommendations concerning use of conventional synthetic (cs) DMARDs (methotrexate (MTX), leflunomide, sulfasalazine); GCs; biological ...

In a swift and decisive military action against terrorist infrastructure in Pakistan and Pakistan-occupied Kashmir (PoK), the Indian armed forces executed Operation Sindoor, where 24 precision ...

Jasson Dominguez launched a towering shot into the second deck in the bottom of the ninth to lift the Yankees past the Rangers with their first walk-off home run since Sept. 20, 2022. That’s a ...

While chronic stress can have profound physiological and emotional effects, temporarily elevated cortisol levels in response to a stressor are normal, said Jaisinghani. Jaisinghani said the cortisol ...

As its exonuclease activity is essential for homologous recombination (HR) and replication fork processing, EXO1 has emerged as a compelling therapeutic target, especially in cancers marked by ...

Center for Molecular Imaging, The University of Michigan Medical School, Ann Arbor, Michigan 48109, United States Department of Radiology, The University of Michigan Medical School, Ann Arbor, ...

measures of quality of life as well as specific changes in blood markers assessing stress response. To our knowledge, this is the first controlled study that shows specific self-reported ...

When stress becomes chronic or ongoing, it triggers a physical response that can quietly take a toll on the body in some ways you might not be aware of. Here are five surprising ways stress can ...