A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...

Mitogen-Activated Protein Kinase (MAPK) signaling pathways play a crucial role in various cellular processes, including growth, differentiation, and response to stress. These pathways are ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

Other brain areas also respond to the threat, and the signals they generate turn on the stress response ... or selective serotonin reuptake inhibitors, such as citalopram (Celexa) and fluoxetine ...

We further analyze the tumor characteristics that result in the development of intrinsic or inherited resistance to BCL-2 inhibitors ... In response to several cytotoxic stimuli, such as developmental ...

Inflammasomes play a crucial role in innate immunity by serving as signaling platforms which deal with a plethora of pathogenic products and cellular products associated with stress and damage ... in ...

Several melanoma cell lines were exposed to inhibitors of Src activity despite ... of melanoma cells through activation of the RAF/MEK/MAPK pathway [4]. Despite the impressive initial responses, ...

Previous research has indicated that MAPK inhibitors could be a potential therapy for NRAS MUT melanoma. However, on their own, MAPK inhibitors fail in about 80% of cases and don't extend patient ...

Previous research has indicated that MAPK inhibitors could be a potential therapy for NRAS MUT melanoma. However, on their own, MAPK inhibitors fail in about 80% of cases and don't extend patient ...

Previous research has indicated that MAPK inhibitors could be a potential therapy for NRASMUT melanoma. However, on their own, MAPK inhibitors fail in about 80% of cases and don’t extend patient ...

A UCLA-led team of researchers used the environmental circumstances and fecal samples collected from the six years prior to the severe El Niño drought in Costa Rica to study the relationship between ...