Old cells are able to revert to a younger state for a better injury response after radically jettisoning ‘waste’ material, rather than managing it through controlled degradation. Cells eject ‘waste’ ...
CRANBURY, N.J.--(BUSINESS WIRE)--Rocket Pharmaceuticals, Inc. (NASDAQ: RCKT), a fully integrated, late-stage biotechnology company advancing a sustainable pipeline of genetic therapies for rare ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The cellular response to lysosomal damage ...
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School of Pharmacy, Huaihe Hospital of Henan University, The Zhongzhou Laboratory for Integrative Biology, State Key Laboratory of Antiviral Drugs, Institute of Chemical Biology, Henan Province ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Reduced autophagy is associated with the ...
State Key Laboratory of Swine and Poultry Breeding Industry, South China Agricultural University, Guangzhou, Guangdong 510642, China Guangdong Academy of Agricultural Sciences, Guangzhou, Guangdong ...
The findings from this study significantly advance our understanding of the unconventional autophagy-mediated secretion of the multifunctional protein PARK7/DJ-1, which is implicated in various ...
Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...
Lysosomes are dynamic organelles integral to cellular homeostasis, secretory pathways, immune responses, and cell death regulation. In cancers, lysosomes become dysregulated to sustain proliferative ...
A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ...
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