A comparative NMR conformational analysis of three distinct tetrapeptide inhibitors of the Hepatitis C NS3 protease that differ at the 4-aryloxy-substituted P2 proline position was undertaken.

The data were analyzed with MaxQuant 1.6.3.4 (Cox & Mann, 2008). MaxQuant settings were as follows: multiplicity 1; fixed modification: carbamidomethyl (C); protease: trypsin with allowed cleavages ...

aYouth Resilience Unit, Academic Unit, Queen Mary University of London, London, UK bCentre for Psychiatry and Mental Health, Wolfson Institute of Population Health, Queen Mary University of London, ...

Edited by Timothy L. Karr, Arizona State University, Tempe, AZ, and accepted by the Editorial Board December 22, 2011 (received for review June 19, 2011) ...

Take Time To Travel 24 Hours in Paris! Champs-Élysées, Arc de Triomphe, Tuileries Garden, Café de la Paix & More! Posted: May 14, 2025 | Last updated: May 14, 2025 Description: We had a ...

Of the two ortho-diamino groups, one is embedded within the acrylamide linker D while the other is a substituent on ring C. The ortho positioning of the amino groups is optimal for zinc binding. When ...

PARIS (AP) — Tour de France riders will climb up the iconic Montmarte hill in Paris on the final stage this year before cycling's biggest race finishes on the Champs-Élysées, organizers said Wednesday ...

Subsequently, 30 µg of cell lysates were loaded onto S-Trap micro columns (ProtiFi, C02-micro); trypsin and lysyl-endopeptidase (Lys-C) solution (1:10 w/w ... containing a complete protease inhibitor ...

Department of Chemistry, Kangwon National University, Chuncheon 24341, Republic of Korea Multidimensional Genomics Research Center, Kangwon National University, Chuncheon 24341, Republic of Korea ...