Researchers from the University of Barcelona and the August Pi y Sunyer Biomedical Research Institute (IDIBAPS) have shown ...

Serotonin can promote both pulmonary vasoconstriction and pulmonary vascular remodeling and is thought to be involved in the pathobiology of PAH. A polymorphism in the serotonin transporter (SERT ...

It is characterized by vasoconstriction and vascular hypertrophy within the pulmonary artery ... phosphodiesterase inhibitors. The mechanisms of action of these agents are summarized in Figure ...

Although the mechanism for the reduction in Vc cannot be determined from these data, passive relocation of blood to the periphery as the result of gravity can be discounted, suggesting that active ...