Thought Leaders Sean Piantadosi Researcher University of Washington What are the roles of norepinephrine and the locus coeruleus (LC) in promoting anxiety-like behavior through the basolateral ...

To varying degrees, this decreased the firing of locus coeruleus neurons and reduced their release of norepinephrine. "The peri-LC cells apparently act like a radio gain circuit that can dial up ...

It gets its distinct blue color from a pigment called neuromelanin, which is formed through chemical reactions involving norepinephrine ... believe the locus coeruleus is the brain region most ...

The locus coeruleus—with its two lobes the size of a grain of ... For instance, the LC’s ability to regulate arousal via norepinephrine release might be able to mask neuronal loss in the hypothalamus ...

It is a literal description: the neurons in the locus coeruleus are dyed the colour of sapphire from the production of a particular neurotransmitter, called norepinephrine. This is also a clue to ...

More recent experiments suggest that the flow process may also involve the locus coeruleus-norepinephrine (LC-NE) system in the brain. This system helps balance task engagement and decision-making, ...

The stem-cell-derived norepinephrine neurons of the type found in a part of the human brain called the locus coeruleus may enable research into many psychiatric and neurodegenerative diseases and ...

Generation of locus coeruleus norepinephrine neurons from human pluripotent stem cells. Nature Biotechnology , 2023; DOI: 10.1038/s41587-023-01977-4 Cite This Page : ...

The stem-cell-derived norepinephrine neurons of the type found in a part of the human brain called the locus coeruleus may enable research into many psychiatric and neurodegenerative diseases and ...

Originating in a small midbrain nucleus, the locus coeruleus (LC), the NA system projects widely throughout the brain. However, the researchers noted, “… our understanding of its role in ...