Having two copies of the ApoE4 gene is not just a risk factor for the development of Alzheimer’s, but is a likely cause of the disease, according to researchers in Spain.

Patients with only one or no copy of ApoE4 are less likely to experience so-called ARIA side effects, like brain swelling and bleeding, associated with amyloid-targeting drugs, than people with ...

Read about the latest research in nutrition. Answers to questions about nutrition, body weight, herbal and nutritional supplements, and the role of diet in improving and maintaining your health.

June 26, 2025 — Hot tubs don't just feel great, they may actually outperform saunas when it comes to health perks. A study found that soaking in hot water raises core body temperature more than ...

Lipoproteins articles from across Nature Portfolio Lipoproteins are large spherical complexes that consist of lipids and proteins. The hydrophobic core consists of triglycerides and a hydrophobic ...

McGill et al. compare the effects of the longevity-promoting compound 17α-estradiol (17αE2) in male mice carrying the common human APOE3 allele versus the Alzheimer-associated APOE4 allele ...

Methods Clarity AD was a double-blind, placebo-controlled, Phase 3 clinical trial evaluating lecanemab in early AD. ARIA was assessed in the following subgroups: by baseline amyloid PET centiloid ...