Leucine and its keto analog 2-oxoisocaproic acid are particularly ... Quantitation of BCAAs by high-performance liquid chromatography (HPLC) and urine organic acid analysis have been available at the ...

Urine colour can provide important diagnostic information. For example, orange urine may indicate a urinary tract infection (UTI), liver disease, or bile duct disorder. Dr Marco Franzoi and ...

Maple syrup urine disease (MSUD ... the mitochondrial BCKDH complex that decarboxylates ketoacid derivatives of leucine, isoleucine, and valine. MSUD can be treated by a strictly controlled ...

Leucine, in particular ... Proper hydration can help dilute urine, reducing the risk of urinary tract infections (UTIs) and other bladder-related issues that are common among older adults.

Urine color changes in early pregnancy When ... that prevents your body from properly breaking down three amino acids: leucine, isoleucine, and valine. When these amino acids build up in your ...

Valine is one of three branched-chain amino acids (BCAA), compounds the body requires to create and maintain proteins, brain chemicals, and hormones. The body can't make its own, so foods that contain ...

“Maple Syrup Urine Disease (MSUD) is a neonatal condition caused by an enzyme deficiency within the cells, which hinders the metabolism of branched-chain amino acids, specifically ...

In this rare inherited genetic metabolic disorder, the body cannot process certain amino acids, especially leucine, causing a harmful build-up of substances in the blood and urine. Amino acids are ...

Leucine is an essential branched-chain amino acid (BCAA) that some research suggests may help improve muscle mass, athletic recovery, inflammation, and blood sugar levels. However, further studies are ...

have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum leucine levels in a mouse model of maple syrup urine ...

What Causes Maple Syrup Urine Disease? Maple syrup syndrome is ... enzymes that break down three amino acids in proteins—leucine, isoleucine, and valine. MSUD is recessive, so you must have ...